Isoglutamine and the growth of Lactobacillus arabinosus.

The esential role of -glutamine in microbial nutrition and metabolism has been well established (Waelsch, 1952). Recently Ayengar et al. (1951) have described in detail the stimulating effect of the amide on the utilization of i-glutamic acid by Lactobacillus arabinosus. However, almost no published data exist which deal with the influence of iisoglutamine on bacterial growth. We wish to describe the growth response of L. arabinosus to Lisoglutamine and also to present evidence for the existence in rat urine of a compound which, in its growth effects on L. arabino*us, resembles iisoglutamine.